Lots lube + experiment a position that suits ur flexibility level for this . One man lies on the bed, you sit down on his penis while facing him, then you lean forward and the second man comes from behind and also puts his penis inside of you.
The answer is, yes, it is possible, but it can be quite painful. If you don't mind the pain, then do proceed slowly and with caution as you do not want to tear the muscles of the rectum. It should be ok to do it occasionally, but doing it too often can stretch the sphincter muscle too much and cause inconsistency or lack of control.
You don't want to get to a situation that are unable to hold your stools and it just falls out. Also make sure that both the penetrators use condoms.